Curriculum Vitae

Sheng-Chieh (Leon) Chiu · Postdoctoral Researcher

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Experience

Postdoctoral Researcher

  • Sovereign AI and digital twin technologies for trustworthy, locally governed clinical AI in neurology and surgery.
  • Cross-modality generative AI: synthesize amyloid PET from structural MRI for burden estimation when PET is unavailable.
  • Foundation-model framework for resting-state fMRI to learn healthy brain dynamics (self-supervised).
  • Real-time computer vision for DaVinci robotic gynecologic surgery: detection and promptable segmentation with visibility-aware tracking.

Graduate Research Assistant

  • Novel image processing and deep learning for amyloid PET quantification in Alzheimer's disease.
  • MRI-assisted and MRI-less DL segmentation pipelines; quantitative equivalence to FreeSurfer across multi-site cohorts.
  • Tracer characteristic-based co-registration for simultaneous PET/MR motion correction.
  • Large-scale stats: Centiloid calibration, equivalence testing, ROC, bootstrap; collaboration across nuclear medicine, radiology, neurology, and CS.

Education

Ph.D. in Biomedical Engineering

GPA: 3.85/4.0

Dissertation: "Optimizing Quantification in Alzheimer's Disease with PET Imaging through Advanced Imaging and Deep Learning Techniques"

B.S. in Biomedical Engineering

GPA: 3.76/4.30 (Upper Division: 3.86/4.30)

Technical Skills

Deep Learning

PythonTensorFlowPyTorch

Medical Imaging

PETMRICo-registrationSegmentationQuantification

Imaging Tools

MATLAB3D SlicerSPMFSLFreeSurferMRIcroGL

Research & Publications

Published

1.

"Amyloid PET quantification with deep learning segmentation models without MRI"

Chiu SC, Lin YC, McConathy J, Lin SY, Fang YHD

Mar 2026, EJNMMI Physics · doi.org/10.1186/s40658-026-00854-8

2.

"Motion correction of simultaneous brain PET/MR images based on tracer uptake characteristics"

Chiu SC, Perucho JA, Fang YHD

Jul 2025, EJNMMI Physics 12(1):75 · doi.org/10.1186/s40658-025-00789-6

In Preparation

·

"Deep learning MR-based segmentation approach for amyloid PET quantification (LEON)"

Chiu SC, Lin YC, McConathy J, Lin SY, Fang YHD

Mar 2026, Target: EJNMMI Physics

Preprint

·

"Prediction of MCI-to-AD progression with atrophy-weighted standard uptake value ratios of ¹⁸F-Florbetapir PET"

Fang YHD, Perucho JA, Chiu SC, Lin YC, McConathy J

Mar 2023, medRxiv · doi.org/10.1101/2023.03.09.23287059

Conference Posters

1.

"Evaluation of Deep Learning Models for Brain Parcellation in Neuroimaging of Alzheimer's Disease"

SNMMI Jun 2024 · View Abstract

2.

"Correction for Involuntary Motion of Simultaneous PET/MR Brain Scans Based on Regional Tracer Characteristics"

SNMMI Jun 2023 · View Abstract

3.

"Deep learning–based image processing and analysis with cloud computing for open-source imaging software"

WMIC Oct 2021 · GitHub

Featured Projects

01

LEON Brain Segmentation

MR-based deep learning segmentation for amyloid PET quantification — diagnostic performance and equivalence to FreeSurfer across large neuroimaging cohorts.

PythonTensorFlowPET/MRI
02

MRI-less Amyloid PET

Deep learning quantification without MRI using synthetic CT for training; equivalent to MRI-based standard and robust on external PET/CT cohorts.

PyTorchPET/CTDeep Learning
03

TCBC Motion Correction

Tracer characteristic–based co-registration for simultaneous PET/MR: reduced misalignment and improved quantification.

MATLABPET/MRRegistration
04

Face Mask Detection

Transfer learning for real-time facial mask detection. PyTorch-based CNN trained on custom dataset.

PythonTransfer LearningVision
05

EmoSpace

Mobile app for emotional regulation and social interaction for children with ASD. Real-time emotion detection and gamified interactions.

UnityMobileASD

Leadership & Activities

Vice President, Taiwanese Student Association at UAB
Jul 2021 – Aug 2022
Led community engagement and cultural events for the Taiwanese student body.
Team Lead, EmoSpace Project
Oct 2018 – Dec 2019
Directed multidisciplinary team developing mobile assistive technology for ASD support.
Executive Secretary, Student Association BME Dept NCKU
Sep 2018 – Jun 2019
Organized department events and managed student association communications.
International Exhibitor, Taiwan Festival in Japan (Sendai)
Mar 2019 – Oct 2019
Represented Taiwan and promoted cultural exchange at international cultural festival.