// Postdoctoral Researcher · NYCU

Sheng-Chieh (Leon) Chiu

Sovereign AI · Neuroimaging · Digital Twin

Sovereign AI and digital twin technologies for neurological and surgical care; amyloid PET/MRI quantification and trustworthy generative neuroimaging.

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Sheng-Chieh (Leon) Chiu

I am a Postdoctoral Researcher at the Digital Medicine and Smart Healthcare Research Center, NYCU, working on sovereign AI and digital twin technologies for healthcare. My research journey began with a deep personal motivation — caring for family members affected by neurodegenerative diseases — and has since grown into a commitment to building trustworthy clinical AI at the intersection of neuroimaging, deep learning, and surgical computer vision.

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Selected research projects and publications

01

LEON Brain Segmentation

MR-based deep learning segmentation for amyloid PET quantification — diagnostic performance and equivalence to FreeSurfer across large neuroimaging cohorts.

Python TensorFlow PET/MRI
02

MRI-less Amyloid PET

Deep learning quantification without MRI using synthetic CT for training; equivalent to MRI-based standard and robust on external PET/CT cohorts.

PyTorch PET/CT Deep Learning
03

TCBC Motion Correction

Tracer characteristic–based co-registration for simultaneous PET/MR: reduced misalignment and improved quantification.

MATLAB PET/MR Registration

Personal reflections on research, growth, and life

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